Job Description
Requisition Id:  2988
Job Title:  Investigator, Protein Sciences
Posting Start Date:  5/9/25
Job Description: 

RESPONSIBILITIES 

 

  • Clone, express, and purify therapeutic antibodies 

  • Characterize antibody candidates for cell binding using FACS and high-content screening (HCS) instruments (Cell Insight CX5 Platform) 

  • Characterize antibody candidates using analytical methods (e.g. SDS-PAGE, SEC, IEF, DSC, DSF, HIC, Nano DSF/DLS)  

  • Develop and perform protein-protein interaction assays, including kinetic, epitope binning, blocking assays (ELISA, SPR, BLI) 

  • Implement new technologies as required to improve efficiency of the group (e.g. AC-SINS, automation of production or DNA preps using TECAN) 

  • Be a hands-on presence in the laboratory 

  • Perform data analysis and documentation 

  • Write formal technical reports, methods and procedures 

  • Accomplish goals under project team timelines 

  • Communicate effectively and in a timely manner protein production status and research progress to senior management 

  • Present results during internal meetings 

  • Support a culture that embraces scientific excellence, continuous learning, and increasing team’s ability to deliver novel drug candidates 

  • Comply with HSE guidelines 

 

EDUCATION AND DESIRED EXPERIENCE 

 

  • MSc or BSc degree in Biochemistry, Structural Biology, Biotechnology or a related discipline is required. Industry experience in antibody characterization is preferred 

  • Proficiency in molecular biology techniques (PCR, cloning, primer design) and DNA sequence analysis software is required. 

  • Hands-on experience in protein production, purification and characterization (practical knowledge of HPLC and/or AKTA protein purification systems is preferred) 

  • Experience with protein-protein interaction methods (SPR, BLI or related technologies), hands-on experience with Biacore and/or Octet systems is desirable 

  • Hands-on experience in cell culture is preferred. 

  • Knowledge in Design of Experiment and statistical analysis is a plus. 

  • Scientific curiosity, problem solving abilities, capacity to plan experiments and analyze results. 

  • Self-motivated team player with strong organization skills. 

  • Able to work with flexibility in a changing and demanding research environment 

  • Professional level in English, both written and verbal. 

 

 

LOCATION: 

 

You will join us, a biotech community at the Biopole