Job Description
Requisition Id:  2987
Job Title:  RA/Investigator - In Vivo Pharmacology
Posting Start Date:  5/7/25
Job Description: 

About Us:

We are an innovative biotechnology company advancing next-generation bispecific antibody therapeutics using our proprietary BEAT platform. Join a team committed to transforming immuno-oncology treatments.

 

RA/Investigator – In Vivo Pharmacology

Department: Immuno-Oncology II

 

Your Mission:

  • Design, execute and analyze in vivo studies to characterize antibody-based therapeutics.
  • Execute hands-on, in vivo work at all stages of animal experimentation, including in-life and ex vivo analysis.
  • Isolate PBMCs and maintain primary human cells (e.g., T cells, NK cells, Monocytes) and cell lines in culture.
  • Perform immune cell-based functional assays using primary human cells.
  • Conduct phenotype analyses, activation or cytotoxicity assay using multicolor flow cytometry and multiplex cytokine profiling (i.e. ELISA, MSD, Luminex).
  • Analyze data using Excel, GraphPad, FlowJo etc.
  • Present findings in team meetings.
  • Ensure compliance with HSE and BSL-2 biosafety standards.
  • Document experiments
  • Support laboratory operations and equipment maintenance.

Your Profile:

  • Technical degree (RA position) or Bachelor/Master degree (Investigator position) with experience in immunology or oncology models in vivo.
  • Strong experience with handling mice is mandatory.
  • Active LTK1 certification is mandatory
  • LTK2 is a plus.
  • Experience in cell culture (human and murine cells) and flow cytometry is mandatory.
  • Proficient in data analysis using standard software.
  • Comfortable working in an English-speaking environment; fluency in French is a plus.
  • Strong organizational and multitasking skills.
  • Effective team player with excellent interpersonal communication skills.
  • Experience with ELISA is a plus
  • Experience with CDX models is highly desirable.
  • Experience with humanized immune system models (CD34 or PBMC) is highly desirable.